Spinal cord injury often causes an irreversible loss of function which is due in part to the damage of the corticospinal tract (CST). Since the CST contributes significantly to the control of skilled ...

Agnes (Yu) Luo, PhD. [University of Cincinnati] After a stroke, extracellular matrix (ECM) molecules known as chondroitin sulfate proteoglycans (CSPGs) become barriers to axonal plasticity and ...

A stroke wreaks havoc in the brain, destroying its cells and the connections between them. Depending on its severity and location, a stroke can impact someone's life forever, affecting motor activity, ...

Looking at brain tissue from mice, monkeys and humans, scientists have found that a molecule known as growth and differentiation factor 10 (GDF10) is a key player in repair mechanisms following stroke ...

The Immense Importance of Brain-Derived Neurotrophic Factor Crossing the Blood-Brain Barrier According to research undertaken by Iughetti et al. (2011), the central nervous system and the peripheral ...