Vitamin B12 is an essential vitamin, and low levels are linked to obesity. B12 shots could improve fatigue if you have a deficiency, but there’s not much research on them as a weight loss treatment.

This article was reviewed by Lynn Marie Morski, MD, JD. Key Takeaways: Tirzepatide with B12 is sometimes combined as a weekly injection for weight loss. Vitamin B12 supplementation may reduce fatigue ...

Medically reviewed by Sohaib Imtiaz, MD Key Takeaways Take vitamin B12 on an empty stomach in the morning or early afternoon to maximize absorption and avoid sleep disruptions.Vegans, older adults, ...

Tirzepatide (Mounjaro®, Zepbound®) is a once-weekly diabetes and weight loss medication. Compounded tirzepatide is sometimes combined with vitamin B12 to provide additional health benefits. We’ll ...