The Buffalo Bills return to Highmark Stadium Sunday looking to build on one of the NFL's hottest starts. After opening the 2026 season with two convincing victories, including a primetime win over the Detroit Lions in the debut of the new Highmark Stadium, the Bills enter Week 3 as one of the AFC's early favorites.

Here are all the highlights from the Bills' 24-16 win vs. the Chargers in Week 3.

A new era will begin in Buffalo when the Bills host the Detroit Lions on Thursday night. The new Highmark Stadium will play host to its first regular-season game, as the Bills said goodbye to their previous home for 53 seasons at the end of the 2025 season.

The Buffalo Bills hosted the Detroit Lions in their first game at their new home, Highmark Stadium. Here are all the highlights from Bills vs. Lions in Buffalo.

Highlights from the Week 4 matchup between the New England Patriots and the Buffalo Bills from the 2026 NFL season.

NFL Week 5 score predictions, picks, betting odds for Los Angeles Rams vs Buffalo Bills game on Monday, Oct. 12, 2026. Who will win NFL Week 5 game?