This review illustrates how the nuclear phosphoinositide-p53 signalosome integrates lipid signaling and p53 function to regulate cancer cell motility. The figure contrasts the tumor-suppressive ...

In this review, the authors present recent findings that uncover a previously unappreciated nuclear signaling hub: the PIPn-p53 signalosome. This complex not only modulates AKT activation within the ...

Researchers from Tokyo Metropolitan University have found that the motion of unlabeled cells can be used to tell whether they are cancerous or healthy. They observed malignant fibrosarcoma cells and ...

A key pressure-sensing protein involved in intestinal movement and inflammation regulation has been identified. Researchers from Harvard Medical School (MA, USA) and the Icahn School of Medicine at ...

PHILADELPHIA ­— Cancer cells’ quick moves may make them skilled escape artists. Some cancer cells appear to wriggle away from immune cells trying to gobble them up. These evasive maneuvers — caught on ...