Weill Cornell Medicine investigators have identified in a preclinical model a specific brain circuit whose inhibition appears to reduce anxiety without side effects. Their work suggests a new target ...

Researchers from the newly-established Center for Neural Circuit Mapping at the University of California, Irvine School of Medicine evaluate the properties of anterograde and retrograde viral tracers, ...

The future of circuit design, encompassing analog, RF/5G, and custom electronic circuits, is set to be revolutionized by the integration of generative AI tools. These advanced tools will not only ...

A research team led by the University of California, Irvine has created 20 new recombinant rabies viral vectors for neural circuit mapping that offer a range of significant advantages over existing ...

A research team has created 20 new recombinant rabies viral vectors for neural circuit mapping that offer a range of significant advantages over existing tools, including the ability to detect ...

This 3D illustration shows color-coded basal ganglia structures. These subcortical brain regions are located beneath the cerebrum's outermost layer of gray matter known as the cerebral cortex. Source: ...

Optogenetic tools such as channelrhodopsin-2 (ChR2) enable the manipulation and mapping of neural circuits. However, ChR2 variants selectively transported down a neuron’s long-range axonal projections ...

Emerging evidence suggests that brain circuits can be therapeutically targeted to treat neurological, neuropsychiatric and neurodevelopmental disorders. To develop such therapeutic approaches in the ...

The study showed that silencing the specific cells that drive this circuit eased chronic pain while preserving acute pain responses—in other words, the body’s ability to signal danger. “A surprise to ...