The Colts' loss clinched playoff spots for the Bills and Chargers. The 49ers had already clinched their spot in the NFC, and the win keeps them alive for an NFC West title and a shot at the No. 1 seed.

The San Francisco 49ers offense is cruising and they were dominant in a win over the Indianapolis Colts. Here are the highlights.

The second half of the NFL season couldn't have gone worse for the Indianapolis Colts. Their starting quarterback suffered a season-ending injury, they lost seven consecutive games, and the star cornerback they traded two first-round picks for played just two full games.

The Jacksonville Jaguars have won the AFC South for the third time in franchise history. They'll host a playoff game for the first time since 2022.