The complement cascade evolved as a primitive surveillance system against pathogens 1. Some of the complement components have distinct antimicrobial activity. The fragments derived from C3 degradation ...
It was called ‘complement’ because it aided the antibacterial activity of antibodies. However, it is now known that the complement system can be activated early in an infection without the presence of ...
To survive in the human host, bacteria have developed many different strategies to escape the innate immune response, including the expression of an extracellular capsule and 'hiding' within host ...
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