Nanowerk

Mutation: Types, Causes, Effects on Genes and Proteins, and Role in Disease

In simple terms: a mutation is a stable change in genetic sequence that can be copied when cells or viruses replicate. Most mutations have no detectable effect, some contribute to disease, and a small ...
Medical Xpress

Persistent DNA damage in healthy cells challenges traditional view of mutations

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...
EurekAlert!

DNA damage can last unrepaired for years, changing our view of mutations

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Gene mutations may explain some spontaneous spinal fluid leaks

Researchers at Cedars-Sinai Health Sciences University and Johns Hopkins University have identified genetic mutations that ...
Medical Xpress

Q&A: How cryptic mitochondrial DNA mutations reveal a hidden layer of the aging process

New research published in Nature Communications into hidden mutations in mitochondrial DNA has uncovered how high mutational levels coincide with later life and link to aging markers. Mitochondria are ...
Yale Environment 360

Change trackers: New consortium to catalog DNA mutations across human lifetime

From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body’s typically efficient DNA repair machinery and potentially affecting our health ...
Phys.org

Scientists use gene editing to correct harmful mitochondrial mutations in human cells

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor. The ...
BioTechniques

Novel tool for detecting hidden genetic mutations

A graph-based computational tool for detecting previously invisible genetic mutations has been developed. Researchers at the University of California, Los Angeles (UCLA; USA) and the University of ...
Nature

Profiling genetic mutations in the DNA damage repair genes of oral squamous cell carcinoma patients from Pakistan

Both males and females of all ages which were clinically and histopathologically confirmed for OSCC (Stage I-IV) were included in this study. Tissue biopsies were collected from patients meeting the ...

Researchers find rare genetic mutation doesn't always result in blood cancer

Researchers have found that a genetic mutation associated with a rare group of blood cancers does not always result in ...
Forbes

Does Smoking Cause Genetic Mutations In Your Children?

A man sits outside and holds a slim menthol cigarette between his fingers. Close-up with focus on the cigarette. The study provided a comprehensive examination of how lifestyle and environmental ...