Oh, the injury bug, a dreaded foe for even the most experienced fantasy football managers. We're only a week into the 2025 NFL season and injuries are already impacting lineup decisions across the fantasy world.

A set of exact Week 2 NFL score predictions can give you the tools needed to make a variety of picks for every game, as well as a guide for some NFL props you could target as well. Hitting on an exact NFL score prediction could also result in a huge payday.

If any NFL owners could “afford” to either forgo PSLs or try to cap PSL costs, it’s the Broncos’ Walton-Penner group.

Can J.J. McCarthy find ways to beat Jessie Bates? Does Juwan Johnson have fantasy appeal? And could James Conner have a big rushing day?

Aside from the Eagles-Chiefs rematch, the league is still buzzing over J.J. McCarthy, Daniel Jones and more heading into Week 2.

The Packers are already 2-0 with wins over a pair of 2024 playoff teams. Can Cincinnati get there, too? And can Patrick Mahomes stave off an 0-2 start despite being a rare home underdog?

On the offensive side of the ball, the Bills have been a top-five unit, ranking best in the NFL by averaging 497.0 yards per game. The Broncos sport the best defense in the NFL with only 133.0 total yards allowed per game.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks its since inception. The model went 33-17 on top-rated picks in 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.