SANTA CLARA, Calif. --San Francisco 49ers defensive end Nick Bosahas a "significant" ankle sprain and will not play in the preseason, general manager John Lynch said Thursday morning. Lynch told KNBR ...

Nick Bosa has been struggling to shake off the injury bug ever since becoming a San Francisco 49er. Bosa re-injured his sprained ankle Sunday against the Tampa Bay Buccaneers, which is why he’s been ...

The way Matthew Stafford and the Los Angeles Rams picked apart the injury-riddled defense for San Francisco, it raised ...

Injured San Francisco stars Fred Warner and Nick Bosa still are showing up for their 49ers teammates despite being out for ...

After the San Francisco 49ers made it out of their loss to the Los Angeles Rams unscathed, coach Kyle Shanahan could breathe ...

The Niners' famously intense Thursday practices have taken a toll this season, but players also credit them for setting the ...

The San Francisco 49ers have ruled out three players against the Los Angeles Rams for Thursday Night Football. Nick Bosa and Isaac Guerendo aren't one of those players. The 49ers have listed Bosa (hip ...

SANTA CLARA, Calif. (AP) — The long string of injuries that have haunted the San Francisco 49ers all season finally became too much to overcome for at least one week. The defense missing its top two ...

The shorthanded San Francisco 49ers are 5-3 before getting set to play the New York Giants in Week 9. More News: Two College ...

Per the 49ers’ official practice report, the defensive line is dealing with even more injuries. After losing both Nick Bosa ...

San Francisco 49ers defensive lineman Mykel Williams will miss the rest of the season after the first-round pick was ...