Relatively little is known about the biologic relevance of numerical chromosomal changes in relation to DNA content in osteosarcoma. In this study, by using a series of human osteosarcoma cell lines, ...
Structural and numerical chromosome abnormalities are an important cause of miscarriage, infertility and congenital anomalies in humans. Aneuploidy is detected in ∼35% of spontaneous abortions and in ...