Malaria pathogenesis is driven by intricate molecular interactions between Plasmodium parasites and human host cells, among which glycosylphosphatidylinositol (GPI) anchors play a pivotal role. GPI ...

Cerebral malaria is one of a number of clinical syndromes associated with infection by human malaria parasites of the genus Plasmodium. The etiology of cerebral malaria derives from sequestration of ...

Malaria pathogenesis reflects a complex interplay between Plasmodium parasites and the host immune system, in which T cells occupy centre stage. CD4+ T helper 1 (Th1) cells drive protective immunity ...

Two hemoglobin mutations, including one that causes sickle cell anemia, may protect people from severe malaria by gumming up the cellular machinery the parasite uses to transmit deadly proteins to the ...

RIVERSIDE, Calif. -- Nearly half the world’s population lives in regions where malaria is endemic, with the parasite Plasmodium falciparum accounting for approximately 95% of malaria-related deaths ...

Researchers report that the discovery of a malaria protein that helps the parasite grow inside red blood cells and plays a key regulatory role in the parasite’s immune evasion tactics could pave the ...

Both sickle cell disease (SCD) and malaria are potentially dangerous conditions that affect red blood cells (RBCs). While certain forms of SCD may increase the risk of severe complications, one type ...

For decades, malaria control has worked by reducing the number of mosquitoes and treating infected people. As a result bed nets, indoor insecticide spraying, and effective medicines have saved ...

Having one copy of the sickle cell gene may help protect you from a malaria infection. But two copies of the gene may increase your risk of death from malaria. Malaria is a potentially life ...

1 Vascular Immunology Unit, Department of Pathology, Sydney Medical School, The University of Sydney, Camperdown NSW 2042, Australia. Cerebral malaria (CM) is a complex of syndromes relating to the ...