Puerto Rico has always brought strong teams into the Caribbean World Series, though they have not won a championship since Criollos de Caguas won back-to-back titles in 2017 and 2018. Indios was one of three teams that finished with a 2-2 record in the opening round, though they lost to Mexico like everyone else did.

The Charros de Jalisco arrive undefeated to the 2025 Caribbean Series semifinals and will face the Indios de Mayagüez of Puerto Rico at Nido de las Águilas Stadium in Baja California.