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Hidden DNA weak spot near gene start mutates rapidly

These sequences are extremely prone to mutations and rank among the most functionally important regions in the entire human genome, together with protein-coding sequences,” said Donate Weghorn, a ...
CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.
Scientists have created the first comprehensive map of DNA quadruplexes, fleeting knot-like structures that play an outsized ...
An international team, including researchers from HSE University, has created the first comprehensive map of ...