In just a few decades, DNA sequencing technologies evolved from slow, manual processes to rapid, automated ones, making ...

DNA sequencing from bulk or clonal human tissues has shown that genetic mosaicism is common and contributes to both cancer and non-cancerous disorders. However, single-cell resolution is required to ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Cornell researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome. Transposons play critical roles in immune response, ...

Fred Sanger was awarded the Nobel Prize in Chemistry in 1980 for the discovery of dideoxynucleotide sequencing of DNA, merely 3 years after a description of the technique was published 1. In the ...

Michigan Tech's Genomic Sequencing Lab, part of the University's Health Research Institute, plays a leading role in tracking animal-borne illnesses in the Upper Peninsula region while also advancing ...

Funding from agencies such as the National Science Foundation, the National Institutes of Health, NASA and many more help ensure the United States remains at the forefront of discoveries in health, ...

Short-read RNA-seq provides robust gene-level expression but is limited in resolving full-length transcripts and splice variants. Long-read sequencing addresses these limitations by capturing complete ...

Students take samples of water and the microscopic creatures within at the Alviso Marina County Park. (Image by Erika Cardema) At the Alviso Marina County Park, reddish-brown water laps at the edge of ...

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. Researchers from the University of Birmingham have uncovered ...

Researchers at the Center for Crop and Disease Management (CCDM) have developed a new system that combines spore trapping with advanced DNA sequencing to confirm fungicide resistance from air samples ...