Madness continues on Thursday with four Sweet 16 games, including No. 1 seed Duke and Cooper Flagg facing No. 4 Arizona.

The Duke and North Carolina women have faced each other 110 times, including 16 games on a neutral court, but they’ve never played in the NCAA Tournament — until Friday.

No. 1 seed Duke, led by National Player of the Year candidate Cooper Flagg, will square off against No. 1 seed Houston, while No. 1 seed Florida faces No. 1 Auburn in the national semifinals. Florida will make its first appearance in the Final Four since 2014.