A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...

A genetic mutation that helps animals like yaks and Tibetan antelopes survive at high altitudes may hold the key to repairing nerve damage in conditions such as cerebral paralysis and multiple ...

By Tarun Sai Lomte Scientists reveal how evolution within our own tissues can drive disease, protect cells, and uncover hidden therapeutic targets for future precision medicine. Somatic genomics ...

A genetic mutation that helps animals like yaks and Tibetan antelopes survive at high altitudes may hold the key to repairing ...

That superhero is a gene called TP53, and for decades scientists have known it as the “guardian of the genome.” In a healthy cell, TP53 acts like both a brake and an emergency stop button. When DNA ...

Cancer death rates in the UK have hit a record low, but the picture is more complicated than the headline figure suggests.

Ferroptosis is a form of cell death driven by iron ions and lipid peroxidation. For the heart, this death process acts like a chain reaction, delivering an irreversible and devastating blow to ...

In people destined to get Alzheimer's in their mid-40s, one protein can delay the onset of the disease by about 20 years.

Researchers at Cardiff University have uncovered how a particularly severe form of DNA damage arises—shedding new light on mutation processes that contribute to cancer and inherited genetic conditions ...

Many of us might reach for the hair dye the moment those first grey hairs appear. But a new study suggests we may be covering up one of the body's most ingenious defences against cancer.

The tiny Amazon molly (Poecilia formosa) has always fascinated researchers because, according to the rules of evolution, it shouldn't have survived as a species, let alone thrive as a species for over ...

Explore the latest colorectal cancer treatment advances, from precision oncology and immunotherapy to ADCs, bispecifics, and T-cell engagers.