The No. 1 Rebels lost 12-11 to No. 4 Murray State on June 2 at Swayze Field. Murray State advances to face Duke (40-19) in a super regional. The Rebels were down 12-3 in the bottom of the seventh but mounted a huge rally. Brayden Randle's three-run home run in the bottom of the eighth reduced the Murray State lead to 12-11.

Ole Miss was down nine runs to Murray State through seventh inning stretch time in the championship game of the 2025 Oxford Regional. Ultimately the eight runs the Rebels scored during the final three innings wasn't enough with Racers coming out on top 12-11.

Luke Mistone and Will Vierling had four hits apiece in Murray State’s 19-hit attack and the Racers won the Oxford Regional by holding off 15th-seeded Ole Miss 12-11 to make their first super regional.