The San Francisco 49ers were expected to beat the Tennessee Titans, and they were expected to do it by about two scores.

The biggest news of the day comes in the health department, as three-time MVP Patrick Mahomes suffered a torn ACL late in the ...

San Francisco 49ers quarterback Brock Purdy connects with tight end George Kittle on back-to-back plays against the Tennessee ...

San Francisco 49ers quarterback Brock Purdy throws to tight end George Kittle who gains 24 yards against the Tennessee Titans ...

Brock Purdy threw a one-yard TD to George Kittle that extended the San Francisco 49ers lead to 31-10 over the Tennessee ...

The 49ers changed Brandon Aiyuk’s status to “reserve/left squad” on Saturday after a season-long mystery of when he might ...

Despite all of the team's injury issues, the San Francisco 49ers (9-4) find themselves just one game behind the NFC ...

"Christian, I still think he's got years left on the legs," Kittle said. "He still looks great. You should see the way that ...

49ers quarterback Brock Purdy has commented on what it’s like to be without trusted wide receiver Brandon Aiyuk, one of his ...

The 49ers (9-4) take on No. 1 overall draft pick Cam Ward and the Tennessee Titans (2-11) on Sunday at Levi’s Stadium.

Ricky Pearsall deployed a nifty double move to make arguably the 49ers’ biggest catch last game. His third-and-long ...

San Francisco 49ers tight end George Kittle is known to have one of the best personalities in the NFL, but football fans ...