Background NDX-1017 is a brain-penetrant small molecule that activates signaling via the hepatocyte growth factor (HGF)/MET receptor system (Moebius and Church, 2023). HGF …

Mar 12, 2025 · O-GlcNAcylation, i.e., addition of N-acetylglucosamine to serine and threonine residues, is a post-translational modification that regulates the function of many proteins. In …

Background Pridopidine, formerly called huntexil, is a selective agonist of the sigma1 receptor, a molecular chaperone located in the endoplasmic reticulum in association with mitochondria. …

SORLA, the sortilin-related receptor with type-A repeats, also known by its gene name SORL1 and as LR11, is an endosomal sorting receptor involved in APP and Aβ trafficking, among …

How would you like to share? Facebook Twitter LinkedIn Back to the Top Find a Therapeutic By Name Go NSC001 AAB-003 AADvac1 AAV-GAD AAV2-BDNF ABBV-1088 ABBV-552 ABBV …

Overview Name: HMTM Synonyms: LMTM, LMTX, LMT-X, TRx0237, Tau aggregation inhibitor (TAI), Methylene BlueChemical Name: Hydromethylthionine mesylate, Leuco-methylthioninium …

Dec 5, 2022 · This common polymorphism was identified in a search for regulators of APOE gene expression (Artiga et al., 1998a). Sequencing nucleotides −1017 to +406 in samples of 75 …

Dec 5, 2022 · Sequencing nucleotides −1017 to +406 in samples of 75 unrelated Spanish individuals, the authors identified three polymorphisms, including c.-494T>C, in the APOE …

Dec 5, 2022 · Sequencing nucleotides −1017 to +406 in samples of 75 unrelated Spanish individuals, the authors identified three new polymorphisms, including c.-286T>G, in the APOE …

Karstens AJ, Christianson TJ, Lundt ES, Machulda MM, Mielke MM, Fields JA, Kremers WK, Graff-Radford J, Vemuri P, Jack CR Jr, Knopman DS, Petersen RC, Stricker NH. Mayo …