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  1. B-cell activating factor - Wikipedia

    BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B /TACI, TNFRSF17 /BCMA, and TNFRSF13C /BAFF-R. This …

  2. The BAFF/APRIL system: Emerging functions beyond B cell biology and ...

    In this review, we provide the latest views on additional roles of the BAFF system in health and diseases, as well as an update on BAFF and autoimmunity, with particular focus on current clinical …

  3. BAFF and BAFF-Receptor in B Cell Selection and Survival

    Oct 8, 2018 · The BAFF-receptor (BAFFR) is encoded by the TNFRSF13 gene and is one of the main pro-survival receptors of B cells. Its function is impressively documented ...

  4. BAFF: A fundamental survival factor for B cells - Nature

    Jul 1, 2002 · BAFF is a survival factor for B cells that controls B-cell maturation. BAFF -deficient mice lack mature B cells. BAFF supports the survival of immature T2 B cells and, possibly, mature B...

  5. The BAFF Protein’s Role in Immune Health and Disease

    Aug 1, 2025 · BAFF is an important cytokine that helps regulate both innate and adaptive immune responses. It is particularly important for the development, survival, and maturation of B cells, which …

  6. B-cell activating factor – Knowledge and References – Taylor & Francis

    B-cell activating factor (BAFF) is a cytokine belonging to the TNF family that is crucial for the generation and maintenance of B cells. It acts as a positive regulator of B-cell activation and antibody production.

  7. B Cell Activating Factor Signaling | GeneGlobe - Qiagen

    B-Cell Activating Factor (BAFF) is a TNF-related ligand that promotes B-Cell survival. It is expressed on dendritic cells, monocytes/macrophages, and T-Cells. BAFF is a positive regulator of B-Cell function, …

  8. Baff - (Immunobiology) - Vocab, Definition, Explanations | Fiveable

    BAFF (B-cell activating factor) is a crucial cytokine that plays an essential role in the survival and differentiation of B cells, particularly in the generation and maintenance of memory B cells.

  9. B-Cell Activating Factor - an overview | ScienceDirect Topics

    sBAFF (B cell activating factor, also known as B cell survival and activation factor), acts as a potent B-cell activator and it has been shown to play a crucial role in the proliferation and differentiation of …

  10. B cell activating factor (BAFF): Structure, functions ... - PubMed

    The B cell activating factor (BAFF), or B lymphocyte stimulator (BLyS), is a B cell survival factor which supports autoreactive B cells and prevents their deletion.