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  1. Trisomy 21 (Down Syndrome) | Children's Hospital of Philadelphia

    What is Trisomy 21 (Down syndrome)? Trisomy 21 is the most common chromosomal anomaly in humans, affecting about 5,000 babies born each year and more than 350,000 people in the United …

  2. Down syndrome - Wikipedia

    Down syndrome or Down's syndrome, [12] also known as Trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. [3] . It is usually associated with …

  3. Down syndrome - Symptoms and causes - Mayo Clinic

    Nov 12, 2024 · Down syndrome is a genetic condition caused when an unusual cell division results in an extra full or partial copy of chromosome 21. This extra genetic material causes the developmental …

  4. Down Syndrome | Birth Defects | CDC

    Jan 8, 2026 · Down syndrome is a condition in which a person has an extra copy of chromosome 21. Chromosomes are small "packages" of genes in the body's cells, which determine how the body …

  5. Down Syndrome - StatPearls - NCBI Bookshelf

    Down syndrome (trisomy 21) is a genetic disorder caused by the presence of all or a portion of a third chromosome 21. Patients typically present with mild to moderate intellectual disability, growth …

  6. Down Syndrome (Trisomy 21) in Children

    Down syndrome is a genetic disorder. It is also called trisomy 21. It includes certain birth defects, learning problems, and facial features. A child with Down syndrome also may have heart defects and …

  7. Trisomy 21: What you need to know - Massachusetts General Hospital

    Trisomy 21 (more commonly known as Down syndrome) is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. Learn how it happens.

  8. Down Syndrome (Trisomy 21) - Children's Health Issues - MSD …

    Down Syndrome (Trisomy 21) - Learn about the causes, symptoms, diagnosis & treatment from the MSD Manuals - Medical Consumer Version.

  9. About Down Syndrome - National Human Genome Research Institute

    Jun 29, 2017 · Trisomy 21 means that each cell in the body has three copies of chromosome 21 instead of the usual two copies. Having an extra number 21 chromosome interrupts the normal course of …

  10. Understanding Trisomy 21, Mosaicism, and Translocation

    2 days ago · Learn the three types of Down syndrome including trisomy 21, mosaicism, and translocation explained in clear, easy-to-understand language.